Protandim Tri-Synergizer

The Protandim Family

LifeVantage is a company using science to approach health differently – we are focused on understanding and addressing the root causes of aging to be able to take a proactive approach to increasing healthspan.

We specialize in Nutrigenomics – using Nutrients to affect gene expression. Put simply, we use nutrients to tell our bodies how to help themselves.

It all started almost half a century ago, when science proved that our bodies have built in abilities to keep themselves healthy. Two decades ago, a discovery proved that we could tap into those abilities by communicating with our genes through nutrients.

That discovery is the reason LifeVantage exists. The discovery that five plant extracts, when used together, could tell your body to produce antioxidants*, opened a whole new world of possibilities. Since then we have been relentlessly working to communicate with additional genes responsible for health, and each subsequent discovery becomes a member of our flagship Protandim line of synergizers.


The discovery that started it all. One of the leading theories of aging is the oxidative stress theory. It is based on the fact that our cells are constantly bombarded by free radicals (we call the subsequent damage “oxidative stress”). Our bodies naturally produce antioxidants to fight oxidative stress, but our antioxidant production begins to decline in our early twenties. Protandim® Nrf2 was sculpted to activate the Nrf2 pathway, a pathway responsible for antioxidant production. With peer-reviewed studies conducted by the likes of Harvard, Ohio State, the American Journal of Physiology and many more, Protandim Nrf2 Synergizer has been shown to reduce oxidative stress by 40% in just 30 days.*


  • Helps the body detoxify genes, keeping the master blueprint of the cell's function intact*
  • Reduces oxidative stress by 40% in just 30 days*
  • Significantly reduces cellular stress through Nrf2 activation*
  • Produces enzymes capable of neutralizing more than 1,000,000 free radicals**
  • Helps to regulate survival genes*
  • Supports the body's natural ability to repair and rejuvenate its own cells*


After Protandim Nrf2 Synergizer, we turned our focus to the mitochondrial theory of aging. It is based on the fact that our mitochondria decline over time or when stressed. And since our mitochondria are literally powering everything in our bodies, from our heartbeat to our brain cells, obviously any decline in power leads to issues. So, we set out to see if we could activate the NRF1 pathway, a pathway responsible for mitochondrial health. After years of research, we launched Protandim® NRF1 Synergizer. Scientifically formulated to help your cells boost mitochondrial function–supporting energy, concentration, focus, and cognitive performance.*


  • Improves performance through energy function*
  • Enhances cellular health - cells function at peak performance*
  • Increases cellular energy (ATP)*


We then turned to the sirtuin theory of aging. This is based on recent discoveries of the importance of proteins called sirtuins. Studies are showing sirtuin activity comes with a cascade of health benefits. Including supporting a healthy vascular system, maintaining cholesterol levels already in the healthy range, supporting the body’s healthy inflammation response, supporting joint health, heightening mental focus, improving mood, motivation, energy, and much more. However sirtuin activity declines as we age (≃60%).

Researchers have discovered that sirtuin activity can be increased through drastic caloric restriction (reducing calories by 40-60%). A typical caloric restriction diet can increase sirtuin activity 94%. Obviously this drastic approach runs the risk of nutrient deficiency and is not recommended without medical supervision.

So, with the knowledge that sirtuin activation requires the molecule NAD, we went to work. Protandim® NAD Synergizer was specifically formulated to target NAD, and has been shown to increase sirtuin activity by 100% in 24 hours, supporting increased health, focus, energy, mental clarity, and mood.*


  • Supports healthy longevity*
  • Supports autophagy (removal of cellular waste)*
  • Improves mental focus and concentration*
  • Supports positive mood and motivation*
  • Boosts mental and physical energy*
  • Supports body's healthy inflammatory response*
  • Maintain cholesterol levels already in the healthy range*
  • Supports healthy vascular system*
  • Item #: 123124

Protandim Tri-Synergizer

Price: $150.99
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